Potential therapies for insomnia, apnea, and other sleep disorders are typically evaluated in animal models with electrophysiological endpoints, in particular using electroencephalogram measures (EEG).  Specific endpoints include:

• Description of sleep architecture (latency and duration of sleep stages)
• Sleep maintenance
• Sleep/ wakefulness cycles
• REM and NREM sleep patterns, including the following parameters:
  • REM
  • NREM
  • Continuity
  • Sleep bout duration

(For an example study protocol [Click here])

(For an example Final Report [Click here])