Preclinical contract research: animal models of neurological disorders:
Preclinical Depression/Anxiety models
The following animal models of anxiety and depression are available in the laboratories of NDI neuroscientists for testing potential therapeutics.
Guinea pig
Maternal separation
For an example study [Click here])
Rat/mouse
Elevated plus-maze
(For an example study [Click here])
Forced swim test
(To see a video [Click here])
Open field
(For an example study [Click here])
Ultra-sonic vocalization
(For an example study [Click here])
Effort-related choice behavior (models motivational symptoms of depression)
(For a description [Click here])
Monkey (ketamine-induced impairment)
For further information on this model, see our NHP studies page
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